Determine the domestic hematology reference range for healthy adults in Sri Lanka

Abstract

Hematology science is a subsection in medical science. It is one of the very useful things to measure the healthiness of a person. There is a standard hematology referential range for each hematology attribute. This standard hematology referential range is built many years ago by considering the Gaussian population. All countries use this standard referential range to measure the healthiness of the people. But lately some countries identify that the referential ranges can be changed according to various reasons and using the standard referential range to measure healthiness is not accurate. Therefore, many countries started researches to find a local hematology referential range for their own countries and successfully established them. Through these researches they able to found other hidden patterns related to hematology. Sri Lanka is not a Gaussian country. Hence, using the same standard hematology referential range maybe not accurate for our country. Therefore, finding a local referential range for the White Blood Cell count is the goal of this research. The compatibility of the standard hematology referential range of white Blood Cell count with Sri Lanka was checked through this research. The dataset used for the research contained 600 records related to the full blood count reports. Next, the dataset was separated as a training dataset and testing dataset. The dataset was analyzed using the WEKA data mining tool. Machine learning algorithms are used to build the model by using the training dataset. Several models are built by using classification algorithms and one model was selected by considering its accuracy. The selected model was evaluated by using the testing dataset. The local referential range for White Blood Cell count is found by using the evaluation. There is a difference between the standard White blood cell referential range and the local white blood cell referential range. Therefore, Applying the standard white blood cell referential range for Sri Lankans may be not accurate.